Check out our latest publication!
“Patients with post-COVID-19 condition show minor blood transcriptomic changes, with altered erythrocyte gene expression in a male subgroup”
Don’t miss our latest publication by Karisola et al. which has been published recently in the Frontiers in Immunology Journal.
This study sought to explore transcriptomic alterations in peripheral blood cells of individuals with post-COVID-19 condition (PCC) and determine whether distinct clinical subgroups with unique gene expression profiles could be identified.
The study cohort consisted of 111 patients with post-COVID-19 condition (PCC) from the SARS-CoV-2 Omicron variant period, including 57 individuals who had recovered (Recov) and 54 who continued to experience persistent symptoms consistent with PCC. Their data were compared to 63 healthy controls (Ctrl) with no known history of SARS-CoV-2 infection. Clinical information encompassed patient evaluations, laboratory findings, comorbidities, and self-reported questionnaires on quality of life and daily functioning. Transcriptomic profiling and cellular deconvolution techniques were applied to total RNA extracted from peripheral blood mononuclear cells (PBMCs).
For further details, read the full article here: Long COVID publications.
Karisola, P., Kanerva, M., Vuokko, A., Liira, H., Wang, S., Kvarnström, K., Varonen, M., Suojalehto, H., & Alenius, H. (2025). Patients with post-COVID-19 condition show minor blood transcriptomic changes, with altered erythrocyte gene expression in a male subgroup. Frontiers in immunology, 16, 1500997. https://doi.org/10.3389/fimmu.2025.1500997
