Symptom persistence and biomarkers in post-COVID-19/chronic fatigue syndrome – results from a prospective observational cohort

New study assessed symptom severity and various biomarkers at three time points post infection (3-8 months, 9-16 months, 17-20 months) in 106 Post-COVID Syndrome (PCS) patients with moderate to severe fatigue and exertional intolerance.

While debilitating PCS may persist beyond 20 months post infection, particularly in patients fulfilling diagnostic criteria for myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS), PCS patients reported an overall health improvement. Inflammatory biomarkers equally decreased in both groups.

Symptom persistence and biomarkers in post-COVID-19/chronic fatigue syndrome – results from a prospective observational cohort | medRxiv