The long-term health outcomes, pathophysiological mechanisms and multidisciplinary management of long COVID

Nature has just published an excellent new review on Long COVID. This article presents the primary challenges concerning biological knowledge gaps and efficient remedies, discussing also the corresponding recommendations.

„Given the multisystemic illness of long COVID, numerous clinical manifestations, including impairment of multiple organs/systems, vascular damage, dysautonomia, and ME/CFS, have been observed in an extensive number of patients. Simultaneously, the foreseeable requirement of health care for sequelae of COVID-19 will continue to grow due to the global pandemic. However, the diagnostic and treatment strategies remain inadequate currently. To address these challenges, a combination of existing laboratory tests, suitable health education, outpatient infrastructure, and clinical trials with rigorous designs are clearly warranted.“

The long-term health outcomes, pathophysiological mechanisms and multidisciplinary management of long COVID | Signal Transduction and Targeted Therapy (nature.com)