Exercise intolerance associated with impaired oxygen extraction in patients with long COVID

Study Highlights:

– Reduced O2 pulse peak % predicted (impaired oxygen extraction) may be a mechanism of chronic fatigue and exercise intolerance in Long COVID.

– The study identified chronotropic intolerance as a potential biomarker in Long COVID.

– In this syndrome, impaired O2 extraction may have contributed to both mental and peripheral muscle fatigue and early exercise termination.

– The study’s authors recommend low-intensity, sub-symptom aerobic exercise to treat Long COVID.

Full publication: Long COVID: pathophysiological factors and abnormalities of coagulation – ScienceDirect