– Reduced O2 pulse peak % predicted (impaired oxygen extraction) may be a mechanism of chronic fatigue and exercise intolerance in Long COVID.
– The study identified chronotropic intolerance as a potential biomarker in Long COVID.
– In this syndrome, impaired O2 extraction may have contributed to both mental and peripheral muscle fatigue and early exercise termination.
– The study’s authors recommend low-intensity, sub-symptom aerobic exercise to treat Long COVID.
Full publication: Long COVID: pathophysiological factors and abnormalities of coagulation – ScienceDirect